ECD/SGT1 抗体 (AA 50-567) (Fluoro550)
Our Local Distributor
北京 101111
Quick Overview for ECD/SGT1 抗体 (AA 50-567) (Fluoro550) (ABIN7987092)
抗原
See all ECD/SGT1 (ECD) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 50-567
-
原理
- Anti-SGT1/ECD Antibody Fluoro550 Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human SGT1/ECD recombinant protein (Position: L50-Q567).
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- ECD/SGT1 (ECD) (Ecdysoneless Homolog (ECD))
-
别名
- ECD
-
背景
-
Background: Protein SGT1 is a protein that in humans is encoded by the ECD gene. Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes. Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins. The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex. May play a role in regulation of pre-mRNA splicing.
Gene Full Name: ecdysoneless cell cycle regulator
-
基因ID
- 11319
-
UniProt
- O95905
-
途径
- Regulation of Carbohydrate Metabolic Process
抗原
-