RAD18 抗体 (AA 1-408) (Fluoro647)
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北京 101111
Quick Overview for RAD18 抗体 (AA 1-408) (Fluoro647) (ABIN7986952)
抗原
See all RAD18 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-408
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原理
- Anti-RAD18 Antibody Fluoro647 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human RAD18 recombinant protein (Position: M1-D408).
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- RAD18 (E3 ubiquitin-protein ligase RAD18 (RAD18))
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别名
- RAD18
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背景
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Background: E3 ubiquitin-protein ligase RAD18 is an enzyme that in humans is encoded by the RAD18 gene. The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.
Gene Full Name: RAD18 E3 ubiquitin protein ligase
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基因ID
- 56852
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UniProt
- Q9NS91
抗原
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