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E2F6 抗体 (Middle Region) (Fluoro647)

This 兔 多克隆 antibody specifically detects E2F6 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7986831
发货至: 中国
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Quick Overview for E2F6 抗体 (Middle Region) (Fluoro647) (ABIN7986831)

抗原

See all E2F6 抗体
E2F6 (E2F Transcription Factor 6 (E2F6))

适用

  • 57
  • 26
  • 22
  • 6
  • 5
  • 5
  • 5
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 45
  • 11
  • 1

克隆类型

  • 34
  • 23
多克隆

标记

  • 39
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This E2F6 antibody is conjugated to Fluoro647

应用范围

  • 43
  • 24
  • 23
  • 15
  • 14
  • 13
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 13
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region

    原理

    Anti-Transcription factor E2F6 E2F6 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the related mouse,rat sequences by one amino acid.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human E2F6, different from the related mouse and rat sequences by one amino acid.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    E2F6 (E2F Transcription Factor 6 (E2F6))

    别名

    E2F6

    背景

    Background: E2F6 (E2F transcription factor 6) also known as E2F-6. Northern blot analysis revealed that E2F6 is expressed as 2 mRNAs, 2.5 and 3.5 kb, in all human tissues and cell lines tested. The predicted human and mouse E2F6 protein sequences are 92% identical. The DNA-binding and dimerization domains of E2F6 are highly related to those of other E2F family members, but this protein lacks the sequences necessary for either transcriptional activation or binding to RB1, p107, or p130. E2F6 can act to repress the transcription of E2F-responsive genes by countering the activity of other E2F complexes. E2F6 contributes to gene silencing in a manner independent of retinoblastoma protein family members. E2F6 is found in a multimeric protein complex that contains MGA and MAX, and thus the complex can bind not only to the E2F binding site but also to MYC- and Brachyury- binding sites. The E2F6 complex preferentially occupies target promoters in G0 cells rather than in G1 cells.

    Gene Full Name: E2F transcription factor 6

    Sequence Similarities: Belongs to the E2F/DP family.

    基因ID

    1876

    UniProt

    O75461
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