DKC1 抗体 (AA 19-447) (Fluoro488)
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北京 101111
Quick Overview for DKC1 抗体 (AA 19-447) (Fluoro488) (ABIN7986681)
抗原
See all DKC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 19-447
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原理
- Anti-DKC1 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human DKC1 shares 94.2%,87.9% amino acid (aa) sequence identity with mouse,rat DKC1,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DKC1 recombinant protein (Position: R19-R447). Human DKC1 shares 94.2% and 87.9% amino acid (aa) sequence identity with mouse and rat DKC1, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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别名
- DKC1
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背景
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Background: This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants.
Gene Full Name: dyskerin pseudouridine synthase 1
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基因ID
- 1736
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UniProt
- O60832
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途径
- Telomere Maintenance
抗原
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