DCLK1 抗体 (AA 1-728)
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Quick Overview for DCLK1 抗体 (AA 1-728) (ABIN7986295)
抗原
See all DCLK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-728
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原理
- Anti-DCLK1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- Human DCLK1 shares 96.4% amino acid (aa) sequence identity with mouse DCLK1.
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产品特性
- Anti-DCLK1 Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DCLK1 recombinant protein (Position: M1-S728). Human DCLK1 shares 96.4% amino acid (aa) sequence identity with mouse DCLK1.
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亚型
- IgG
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anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibody
DCLK1 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6H4 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 690-720) antibodyDCLK1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB3161 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 143-381) antibodyDCLK1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyKD Validated DCLK1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 24GB4805 unconjugated Recombinant Antibody
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 1-30), (N-Term) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB3059 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 390-647) antibodyDCLK1 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) antibodyDCLK1 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 1751CT665-1-72 unconjugated
anti-Doublecortin-Like Kinase 1 (DCLK1) (AA 640-729) antibodyDCLK1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6F9 unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- DCLK1 (Doublecortin-Like Kinase 1 (DCLK1))
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别名
- DCLK1
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背景
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Background: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.
Gene Full Name: doublecortin like kinase 1
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分子量
- 85 kDa
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基因ID
- 9201
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UniProt
- O15075
抗原
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