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ERCC5 抗体 (AA 115-964) (FITC)

The 兔 多克隆 anti-ERCC5 antibody is suitable to detect ERCC5 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7985956
发货至: 中国
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Quick Overview for ERCC5 抗体 (AA 115-964) (FITC) (ABIN7985956)

抗原

See all ERCC5 抗体
ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

适用

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人, 小鼠, 大鼠

宿主

  • 50
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克隆类型

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多克隆

标记

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This ERCC5 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 115-964

    原理

    Anti-XPG/ERCC5 Antibody FITC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human XPG,ERCC5 shares 66.6% amino acid (aa) sequence identity with mouse XPG,ERCC5.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human XPG/ERCC5 recombinant protein (Position: K115-R964). Human XPG/ERCC5 shares 66.6% amino acid (aa) sequence identity with mouse XPG/ERCC5.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))

    别名

    ERCC5

    背景

    Background: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.

    Gene Full Name: ERCC excision repair 5, endonuclease

    基因ID

    2073

    UniProt

    P28715

    途径

    DNA Damage Repair
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