ERCC5 抗体 (AA 115-964) (FITC)
Our Local Distributor
北京 101111
Quick Overview for ERCC5 抗体 (AA 115-964) (FITC) (ABIN7985956)
抗原
See all ERCC5 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 115-964
-
原理
- Anti-XPG/ERCC5 Antibody FITC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- Human XPG,ERCC5 shares 66.6% amino acid (aa) sequence identity with mouse XPG,ERCC5.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human XPG/ERCC5 recombinant protein (Position: K115-R964). Human XPG/ERCC5 shares 66.6% amino acid (aa) sequence identity with mouse XPG/ERCC5.
-
亚型
- IgG
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
-
别名
- ERCC5
-
背景
-
Background: This gene encodes a single-strand specific DNA endonuclease that makes the 3' incision in DNA excision repair following UV-induced damage. The protein may also function in other cellular processes, including RNA polymerase II transcription, and transcription-coupled DNA repair. Mutations in this gene cause xeroderma pigmentosum complementation group G (XP-G), which is also referred to as xeroderma pigmentosum VII (XP7), a skin disorder characterized by hypersensitivity to UV light and increased susceptibility for skin cancer development following UV exposure. Some patients also develop Cockayne syndrome, which is characterized by severe growth defects, cognitive disability, and cachexia. Read-through transcription exists between this gene and the neighboring upstream BIVM (basic, immunoglobulin-like variable motif containing) gene.
Gene Full Name: ERCC excision repair 5, endonuclease
-
基因ID
- 2073
-
UniProt
- P28715
-
途径
- DNA Damage Repair
抗原
-