DNMT1 抗体 (AA 509-1577) (HRP)
Our Local Distributor
北京 101111
Quick Overview for DNMT1 抗体 (AA 509-1577) (HRP) (ABIN7985868)
抗原
See all DNMT1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 509-1577
-
原理
- Anti-Dnmt1 Antibody HRP Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived mouse Dnmt1 recombinant protein (Position: Q509-Q1577).
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))
-
别名
- Dnmt1
-
背景
-
Background: DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.
Gene Full Name: DNA methyltransferase 1
-
基因ID
- 13433
-
UniProt
- P13864
-
途径
- SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-