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DNMT1 抗体 (AA 509-1577) (HRP)

This 兔 多克隆 antibody specifically detects DNMT1 in WB, IHC 和 ELISA. It exhibits reactivity toward 小鼠.
产品编号 ABIN7985868
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DNMT1 抗体 (AA 509-1577) (HRP) (ABIN7985868)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

适用

  • 204
  • 64
  • 41
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  • 1
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  • 1
小鼠

宿主

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  • 44
  • 1
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克隆类型

  • 149
  • 70
多克隆

标记

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This DNMT1 antibody is conjugated to HRP

应用范围

  • 128
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 21
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    • 12
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    • 12
    • 10
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    • 5
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    • 1
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    AA 509-1577

    原理

    Anti-Dnmt1 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Dnmt1 recombinant protein (Position: Q509-Q1577).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    Dnmt1

    背景

    Background: DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

    Gene Full Name: DNA methyltransferase 1

    基因ID

    13433

    UniProt

    P13864

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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