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DNMT1 抗体 (AA 509-1577) (Fluoro550)

This 兔 多克隆 antibody specifically detects DNMT1 in FACS. It exhibits reactivity toward 小鼠.
产品编号 ABIN7985865
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for DNMT1 抗体 (AA 509-1577) (Fluoro550) (ABIN7985865)

抗原

See all DNMT1 抗体
DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

适用

  • 204
  • 64
  • 41
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  • 1
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  • 1
小鼠

宿主

  • 173
  • 44
  • 1
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克隆类型

  • 149
  • 70
多克隆

标记

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This DNMT1 antibody is conjugated to Fluoro550

应用范围

  • 129
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  • 21
  • 16
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Flow Cytometry (FACS)
  • 抗原表位

    • 21
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    • 1
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    AA 509-1577

    原理

    Anti-Dnmt1 Antibody Fluoro550 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived mouse Dnmt1 recombinant protein (Position: Q509-Q1577).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DNMT1 (DNA (Cytosine-5)-Methyltransferase 1 (DNMT1))

    别名

    Dnmt1

    背景

    Background: DNA (cytosine-5)-methyltransferase 1 is an enzyme that in humans is encoded by the DNMT1 gene. This gene encodes an enzyme that transfers methyl groups to cytosine nucleotides of genomic DNA. This protein is the major enzyme responsible for maintaining methylation patterns following DNA replication and shows a preference for hemi-methylated DNA. Methylation of DNA is an important component of mammalian epigenetic gene regulation. Aberrant methylation patterns are found in human tumors and associated with developmental abnormalities. Variation in this gene has been associated with cerebellar ataxia, deafness, and narcolepsy, and neuropathy, hereditary sensory, type IE. Alternative splicing results in multiple transcript variants.

    Gene Full Name: DNA methyltransferase 1

    基因ID

    13433

    UniProt

    P13864

    途径

    SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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