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DNMT3B 抗体 (AA 271-853) (PE)

This 兔 多克隆 antibody specifically detects DNMT3B in FACS. It exhibits reactivity toward 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN7985826
发货至: 中国
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Quick Overview for DNMT3B 抗体 (AA 271-853) (PE) (ABIN7985826)

抗原

See all DNMT3B 抗体
DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

适用

  • 150
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  • 1
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人, 小鼠, 大鼠, 猴

宿主

  • 148
  • 6
  • 1
  • 1

克隆类型

  • 130
  • 26
多克隆

标记

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  • 1
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This DNMT3B antibody is conjugated to PE

应用范围

  • 105
  • 79
  • 45
  • 33
  • 22
  • 18
  • 13
  • 10
  • 4
  • 2
  • 2
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 17
    • 16
    • 13
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    • 8
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    • 5
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    • 1
    • 1
    • 1
    AA 271-853

    原理

    Anti-DNMT3B Antibody PE Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DNMT3B recombinant protein (Position: E271-E853).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    DNMT3B (DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B))

    别名

    DNMT3B

    背景

    Background: DNA (cytosine-5-)-methyltransferase 3 beta, is an enzyme that in humans in encoded by the DNMT3B gene. CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

    Gene Full Name: dynamin 2

    基因ID

    1789

    UniProt

    P50570
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