DLG1 抗体 (AA 1-165) (Cy3)
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Quick Overview for DLG1 抗体 (AA 1-165) (Cy3) (ABIN7985630)
抗原
See all DLG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-165
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原理
- Anti-SAP97/DLG1 Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human SAP97 shares 89.7%,84.2% amino acid (aa) sequence identity with mouse,rat SAP97,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human SAP97 recombinant protein (Position: M1-A165). Human SAP97 shares 89.7% and 84.2% amino acid (aa) sequence identity with mouse and rat SAP97, respectively.
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亚型
- IgG
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DLG1 (Discs, Large Homolog 1 (DLG1))
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别名
- DLG1
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背景
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Background: Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength.
Gene Full Name: discs large MAGUK scaffold protein 1
Sequence Similarities: Belongs to the MAGUK family.
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基因ID
- 1739
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UniProt
- Q12959
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途径
- Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
抗原
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