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Dihydrofolate Reductase 抗体 (AA 2-187) (Fluoro594)

The Fluoro594-conjugated 小鼠 单克隆 anti-Dihydrofolate Reductase antibody (Clone 3C8) (ABIN7985261) specifically detects Dihydrofolate Reductase in FACS. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN7985261
发货至: 中国
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Quick Overview for Dihydrofolate Reductase 抗体 (AA 2-187) (Fluoro594) (ABIN7985261)

抗原

See all Dihydrofolate Reductase (DHFR) 抗体
Dihydrofolate Reductase (DHFR)

适用

  • 85
  • 52
  • 46
  • 1
  • 1
人, 大鼠

宿主

  • 70
  • 19
小鼠

克隆类型

  • 54
  • 35
单克隆

标记

  • 38
  • 6
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dihydrofolate Reductase antibody is conjugated to Fluoro594

应用范围

  • 50
  • 33
  • 27
  • 19
  • 16
  • 11
  • 9
  • 6
  • 3
  • 2
Flow Cytometry (FACS)

克隆位点

3C8
  • 抗原表位

    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 2-187

    原理

    Anti-DHFR Antibody (monoclonal, 3C8) Fluoro594 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human DHFRshares90%aminoacid (aa)sequenceidentitywith both mouseandrat DHFR.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DHFR recombinant protein (Position: V2-D187). Human DHFRshares90%aminoacid (aa)sequenceidentitywith both mouseandrat DHFR.

    亚型

    IgG2b
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Dihydrofolate Reductase (DHFR)

    别名

    DHFR

    背景

    Background: SHC, also known as SHC1 (SHC-transforming protein 1) or SHCA, is a protein that in humans is encoded by the SHC1 gene. SCOP classifies the 3D structure as belonging to the SH2 domain family. This gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex. p66Shc is not involved in Ras activation. Unlike the other two isoforms, p46Shc is targeted to the mitochondrial matrix. Several transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: dihydrofolate reductase

    基因ID

    1719

    UniProt

    P00374

    途径

    Mitotic G1-G1/S Phases
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