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Dihydrofolate Reductase 抗体 (AA 2-187) (FITC)

The 兔 多克隆 anti-Dihydrofolate Reductase antibody is suitable to detect Dihydrofolate Reductase in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7985251
发货至: 中国
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Quick Overview for Dihydrofolate Reductase 抗体 (AA 2-187) (FITC) (ABIN7985251)

抗原

See all Dihydrofolate Reductase (DHFR) 抗体
Dihydrofolate Reductase (DHFR)

适用

  • 85
  • 52
  • 45
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 69
  • 20

克隆类型

  • 53
  • 36
多克隆

标记

  • 38
  • 6
  • 4
  • 4
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This Dihydrofolate Reductase antibody is conjugated to FITC

应用范围

  • 50
  • 33
  • 27
  • 19
  • 16
  • 11
  • 9
  • 6
  • 3
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 28
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 2-187

    原理

    Anti-Dihydrofolate reductase (DHFR) Antibody FITC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human DHFR shares 90% amino acid (aa) sequence identity with both mouse,rat DHFR.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DHFR recombinant protein (Position: V2-D187). Human DHFR shares 90% amino acid (aa) sequence identity with both mouse and rat DHFR.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Dihydrofolate Reductase (DHFR)

    别名

    DHFR

    背景

    Background: Dihydrofolate reductase, or DHFR, is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, using NADPH as electron donor, which can be converted to the kinds of tetrahydrofolate cofactors used in 1-carbon transfer chemistry. In humans, the DHFR enzyme is encoded by the DHFR gene. It is found in the q11→q22 region of chromosome 5. What's more, DHFR belongs to the dihydrofolate reductase family, and it converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. DHFR is the key enzyme in folate metabolism. In addition, DHFR catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

    Gene Full Name: dihydrofolate reductase

    Sequence Similarities: Belongs to the dihydrofolate reductase family.

    基因ID

    1719

    UniProt

    P00374

    途径

    Mitotic G1-G1/S Phases
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