DLL3 抗体 (C-Term) (Cy3)
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北京 101111
Quick Overview for DLL3 抗体 (C-Term) (Cy3) (ABIN7984776)
抗原
See all DLL3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-Delta-like protein 3 DLL3 Antibody Cy3 Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human DLL3.
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亚型
- IgG
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anti-delta Like Protein 3 (DLL3) (AA 545-573), (C-Term) antibody
DLL3 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB31357 unconjugated
anti-delta Like Protein 3 (DLL3) (AA 519-548), (C-Term) antibodyDLL3 适用: 人, 小鼠, 大鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB23871 unconjugated
anti-delta Like Protein 3 (DLL3) antibodyDLL3 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-delta Like Protein 3 (DLL3) (AA 27-492) antibodyDLL3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-delta Like Protein 3 (DLL3) (AA 519-548) antibodyDLL3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-delta Like Protein 3 (DLL3) (AA 100-150) antibodyDLL3 适用: 人, 小鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-delta Like Protein 3 (DLL3) antibodyDLL3 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-delta Like Protein 3 (DLL3) (AA 526-556), (C-Term) antibodyDLL3 适用: 人 WB, IF, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, 1-3 μg/1x106 cells
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- DLL3 (delta Like Protein 3 (DLL3))
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别名
- DLL3
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背景
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Background: DLL3 (DELTA-LIKE 3) also known as DELTA, DROSOPHILA, HOMOLOG OF, is a protein which in humans is encoded by the DLL3 gene. This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutation in the mouse delta-like 3 gene (Dll3), which is homologous to the Notch-ligand delta in Drosophila, results in the mouse 'pudgy' phenotype. The human DLL3 gene was identified within a critical interval, mapped in 2 consanguineous Arab-Israeli and Pakistani SCDO1 pedigrees, of 7.8 cM at 19q13.1-q13.3 between D19S570 and D19S908 (Bulman et al., 2000). Dunwoodie et al. (1997) presented results suggesting that mouse Dll3 may complement the function of other delta homologs during early pattern formation in the mouse embryo. In humans, the fact that mutations in genes required for oscillation, such as DLL3, result in abnormal segmentation of the vertebral column suggests that the segmentation clock also acts during human embryonic development. This residue is highly conserved in Delta proteins from Drosophila to humans, and the substitution of a charged polar for a nonpolar residue may disrupt the conformation of the DLL3 protein.
Gene Full Name: delta like canonical Notch ligand 3
Sequence Similarities: Contains 1 DSL domain.
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基因ID
- 10683
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UniProt
- Q9NYJ7
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途径
- Notch Signaling
抗原
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