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DAXX 抗体 (AA 56-345)

Name: DAXX 抗体 (AA 56-345)
SKU: ABIN7984524
Availability: OutOfStock

This 兔多克隆 antibody specifically detects DAXX in WB, IHC, IF, FACS 和 ICC. It exhibits reactivity toward 人, 小鼠和大鼠.

产品编号 ABIN7984524

发货至: 中国

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中国
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Quick Overview for DAXX 抗体 (AA 56-345) (ABIN7984524)

抗原

See all DAXX 抗体

DAXX (Death-Domain Associated Protein (DAXX))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This DAXX antibody is un-conjugated

应用范围

Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

质量等级

Carrier-free

Discover our top product DAXX Primary Antibody

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AA 56-345

原理

Anti-Daxx Antibody

特异性

No cross reactivity with other proteins.

交叉反应（详细）

No cross-reactivity with other proteins

预测反应

Human Daxx shares 88.3%,88.6% amino acid (aa) sequence identity with mouse,rat Daxx,respectively.

产品特性

Anti-Daxx Antibody. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Daxx recombinant protein (Position: K56-R345). Human Daxx shares 88.3% and 88.6% amino acid (aa) sequence identity with mouse and rat Daxx, respectively.

亚型

IgG
anti-Death-Domain Associated Protein (DAXX) (AA 561-660) antibody
DAXX 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 4C2 unconjugated

anti-Death-Domain Associated Protein (DAXX) (AA 56-345) antibody
DAXX 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated

anti-Death-Domain Associated Protein (DAXX) antibody
DAXX 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7A11 unconjugated

anti-Death-Domain Associated Protein (DAXX) (AA 558-740), (C-Term) antibody
DAXX 适用: 人 WB, ICC 宿主: 小鼠 Monoclonal DAXX-01 unconjugated

anti-Death-Domain Associated Protein (DAXX) antibody
KD Validated DAXX 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB795 unconjugated Recombinant Antibody

anti-Death-Domain Associated Protein (DAXX) (C-Term) antibody
DAXX 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Death-Domain Associated Protein (DAXX) (pSer213) antibody
DAXX 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Death-Domain Associated Protein (DAXX) (pSer495) antibody
DAXX 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Death-Domain Associated Protein (DAXX) (AA 1-740) antibody
DAXX 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Death-Domain Associated Protein (DAXX) (pSer213) antibody
DAXX 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB6929 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat Immunocytochemistry , 0.5-1 μg/mL, Human Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

DAXX (Death-Domain Associated Protein (DAXX))

别名

DAXX

背景

Background: DAXX (death-domain associated protein) also known as DAP6 (Death-associated protein 6) or BING2, was first discovered through its cytoplasmic interaction with the classical death receptor Fas. Human DAXX encodes a 740-amino acid polypeptide containing a nuclear localization signal. Functional analyses by Yang et al. (1997) demonstrated that Daxx binds to the Fas death domain and enhances Fas-mediated apoptosis. The authors suggested that DAXX and FADD define 2 distinct apoptotic pathways downstream of Fas. The DAXX gene is mapped to human chromosome 6p21.3 by somatic cell hybrid panels and fluorescence in situ hybridization, a region containing the HLA and putative autoimmune disease genes. MSP58 overexpression relieved DAXX-mediated transcriptional repression. Immunoprecipitation and Western blot analysis with DAXX mutants showed that the N terminus of DAXX interacts with the C terminus of DMAP. Transient expression of DAXX or DMAP1 caused repression of glucocorticoid receptor-mediated transcription.
Gene Full Name: death domain associated protein
Sequence Similarities: Belongs to the DAXX family.

分子量

115 kDa

基因ID

1616

UniProt

Q9UER7

途径

Intracellular Steroid Hormone Receptor Signaling Pathway