DDHD1 抗体 (AA 63-711)
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北京 101111
Quick Overview for DDHD1 抗体 (AA 63-711) (ABIN7983937)
抗原
See all DDHD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 63-711
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原理
- Anti-DDHD1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-DDHD1 Antibody. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human DDHD1 recombinant protein (Position: P63-S711).
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亚型
- IgG
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anti-DDHD Domain Containing 1 (DDHD1) (AA 1-872) antibody
DDHD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-DDHD Domain Containing 1 (DDHD1) (AA 1-872) antibodyDDHD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DDHD Domain Containing 1 (DDHD1) (AA 50-100) antibodyDDHD1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for six months. Avoid repeated freezing and thawing. -
有效期
- 12 months
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- DDHD1 (DDHD Domain Containing 1 (DDHD1))
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别名
- DDHD1
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背景
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Background: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: DDHD domain containing 1
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分子量
- 110 kDa
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基因ID
- 80821
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UniProt
- Q8NEL9
抗原
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