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DDHD1 抗体 (AA 63-711) (HRP)

The HRP-conjugated 兔 多克隆 anti-DDHD1 antibody (ABIN7983944) specifically detects DDHD1 in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7983944
发货至: 中国
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Quick Overview for DDHD1 抗体 (AA 63-711) (HRP) (ABIN7983944)

抗原

See all DDHD1 抗体
DDHD1 (DDHD Domain Containing 1 (DDHD1))

适用

人, 小鼠, 大鼠

宿主

  • 21
  • 1

克隆类型

  • 22
多克隆

标记

  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DDHD1 antibody is conjugated to HRP

应用范围

  • 10
  • 7
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 11
    • 3
    • 1
    AA 63-711

    原理

    Anti-DDHD1 Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DDHD1 recombinant protein (Position: P63-S711).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    DDHD1 (DDHD Domain Containing 1 (DDHD1))

    别名

    DDHD1

    背景

    Background: This gene is a member of the intracellular phospholipase A1 gene family. The protein encoded by this gene preferentially hydrolyzes phosphatidic acid. It is a cytosolic protein with some mitochondrial localization, and is thought to be involved in the regulation of mitochondrial dynamics. Overexpression of this gene causes fragmentation of the tubular structures in mitochondria, while depletion of the gene results in mitochondrial tubule elongation. Deletion of this gene in male mice caused fertility defects, resulting from disruption in the organization of the mitochondria during spermiogenesis. In humans, mutations in this gene have been associated with hereditary spastic paraplegia (HSP), also known as Strumpell-Lorrain disease, or, familial spastic paraparesis (FSP). This inherited disorder is characterized by progressive weakness and spasticity of the legs. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Gene Full Name: DDHD domain containing 1

    基因ID

    80821

    UniProt

    Q8NEL9
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