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DDB2 抗体 (AA 1-115) (HRP)

This 兔 多克隆 antibody specifically detects DDB2 in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7983759
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDB2 抗体 (AA 1-115) (HRP) (ABIN7983759)

抗原

See all DDB2 抗体
DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

适用

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宿主

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克隆类型

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多克隆

标记

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This DDB2 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 1-115

    原理

    Anti-DDB2 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human DDB2 shares 58.3% amino acid (aa) sequence identity with mouse DDB2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human DDB2 recombinant protein (Position: M1-T115). Human DDB2 shares 58.3% amino acid (aa) sequence identity with mouse DDB2.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))

    别名

    DDB2

    背景

    Background: DNA damage-binding protein 2 is a protein that in humans is encoded by the DDB2 gene. This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. And this subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: damage specific DNA binding protein 2

    基因ID

    1643

    UniProt

    Q92466

    途径

    DNA Damage Repair
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