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CYBB 抗体 (AA 416-527) (Biotin)

This 兔 多克隆 antibody specifically detects CYBB in WB, ELISA 和 IHC. It exhibits reactivity toward 人.
产品编号 ABIN7982814
发货至: 中国
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Quick Overview for CYBB 抗体 (AA 416-527) (Biotin) (ABIN7982814)

抗原

See all CYBB 抗体
CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

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宿主

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克隆类型

  • 96
  • 22
多克隆

标记

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This CYBB antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 416-527

    原理

    Anti-NOX2/gp91phox/CYBB Antibody Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human NOX2/gp91phox/CYBB recombinant protein (Position: F416-H527).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

    别名

    CYBB

    背景

    Background: NOX2(NADPH OXIDASE 2), also called CYBB(CYTOCHROME b(-245), BETA SUBUNIT), p91-PHOX or GP91-1, is a human gene encoding a glycoprotein. NOX2 is an essential component of phagocytic NADPH-oxidase, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation. It is mapped on Xp11.4. NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, and that reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes. As a major player in innate immune responses in neutrophils, NOX2 is also involved in adaptive immunity through its activity in DCs. In heart cells, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling).

    Gene Full Name: cytochrome b-245 beta chain

    基因ID

    1536

    UniProt

    P04839
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