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CYBB 抗体 (AA 416-500) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-CYBB antibody (ABIN7982801) specifically detects CYBB in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7982801
发货至: 中国
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Quick Overview for CYBB 抗体 (AA 416-500) (Fluoro647) (ABIN7982801)

抗原

See all CYBB 抗体
CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

适用

  • 118
  • 64
  • 62
  • 18
  • 16
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 104
  • 12
  • 2

克隆类型

  • 96
  • 22
多克隆

标记

  • 41
  • 9
  • 7
  • 7
  • 6
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CYBB antibody is conjugated to Fluoro647

应用范围

  • 60
  • 56
  • 35
  • 24
  • 13
  • 13
  • 11
  • 9
  • 6
  • 5
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 16
    • 13
    • 13
    • 12
    • 11
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 416-500

    原理

    Anti-NOX2/gp91phox/CYBB Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human NOX2/gp91phox recombinant protein (Position: F416-D500).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

    别名

    CYBB

    背景

    Background: NOX2 (NADPH OXIDASE 2), also called CYBB (CYTOCHROME b (-245), BETA SUBUNIT), p91-PHOX or GP91-1, is a human gene encoding a glycoprotein. NOX2 is an essential component of phagocytic NADPH-oxidase, a membrane-bound enzyme complex that generates large quantities of microbicidal superoxide and other oxidants upon activation. It is mapped on Xp11.4. NOX2 assembled on DC phagosomes in a gp91-phox subunit-dependent manner, and that reactive oxygen species were produced in a more sustained manner in immature DC phagosomes than in macrophage phagosomes. As a major player in innate immune responses in neutrophils, NOX2 is also involved in adaptive immunity through its activity in DCs. In heart cells, physiologic stretch rapidly activates reduced-form NOX2 to produce reactive oxygen species (ROS) in a process dependent on microtubules (X-ROS signaling).

    Gene Full Name: cytochrome b-245 beta chain

    基因ID

    1536

    UniProt

    P04839
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