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CYLD 抗体 (AA 618-956) (Fluoro488)

This 兔 多克隆 antibody specifically detects CYLD in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7982574
发货至: 中国
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Quick Overview for CYLD 抗体 (AA 618-956) (Fluoro488) (ABIN7982574)

抗原

See all CYLD 抗体
CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

适用

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人, 大鼠

宿主

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克隆类型

  • 50
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多克隆

标记

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This CYLD antibody is conjugated to Fluoro488

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 618-956

    原理

    Anti-CYLD Antibody Fluoro488 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CYLD shares 97.6%,97.9% amino acid (aa) sequence identity with mouse,rat CYLD,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

    别名

    CYLD

    背景

    Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

    Gene Full Name: CYLD lysine 63 deubiquitinase

    Sequence Similarities: Belongs to the peptidase C19 family.

    基因ID

    1540

    UniProt

    Q9NQC7

    途径

    Apoptosis, Activation of Innate immune Response
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