CDK9 抗体 (AA 141-372) (HRP)
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北京 101111
Quick Overview for CDK9 抗体 (AA 141-372) (HRP) (ABIN7982468)
抗原
See all CDK9 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 141-372
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原理
- Anti-Cdk9 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse,rat Cdk9.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human Cdk9 recombinant protein (Position: H141-F372). Human Cdk9 shares 99.1% amino acid (aa) sequence identity with both mouse and rat Cdk9.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- CDK9 (Cyclin-Dependent Kinase 9 (CDK9))
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别名
- CDK9
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背景
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Background: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-ed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.
Gene Full Name: cyclin dependent kinase 9
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
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基因ID
- 1025
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UniProt
- P50750
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途径
- Cell Division Cycle
抗原
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