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CDK8 抗体 (APC)

The 兔 多克隆 anti-CDK8 antibody is suitable to detect CDK8 in samples from 人. It has been validated for FACS.
产品编号 ABIN7982458
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CDK8 抗体 (APC) (ABIN7982458)

抗原

See all CDK8 抗体
CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

适用

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宿主

  • 97
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克隆类型

  • 78
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多克隆

标记

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This CDK8 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 原理

    Anti-CDK8 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Cdk8 recombinant protein (K355-Y464).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CDK8 (Cyclin-Dependent Kinase 8 (CDK8))

    别名

    CDK8

    背景

    Background: Cell division protein kinase 8 is an enzyme that in humans is encoded by the CDK8 gene. It is mapped to 13q12.13. This gene encodes a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit, cyclin C, are components of the Mediator transcriptional regulatory complex, involved in both transcriptional activation and repression by phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II. This kinase regulates transcription by targeting the cyclin-dependent kinase 7 subunits of the general transcription initiation factor IIH, thus providing a link between the Mediator complex and the basal transcription machinery. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.

    Gene Full Name: cyclin dependent kinase 8

    基因ID

    1024

    UniProt

    P49336

    途径

    Cell Division Cycle, Regulation of Lipid Metabolism by PPARalpha
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