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CDK2 抗体 (AA 81-298) (Cy3)

The Cy3-conjugated 小鼠 单克隆 anti-CDK2 antibody (Clone 5B12D1) (ABIN7982309) specifically detects CDK2 in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7982309
发货至: 中国
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Quick Overview for CDK2 抗体 (AA 81-298) (Cy3) (ABIN7982309)

抗原

See all CDK2 抗体
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CDK2 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)

克隆位点

5B12D1
  • 抗原表位

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    AA 81-298

    原理

    Anti-Cdk2 Antibody (monoclonal, 5B12D1) Cy3 Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cdk2 recombinant protein (Position: E81-L298). Human Cdk2 shares 98.6% amino acid (aa) sequence identity with rat Cdk2.

    亚型

    IgG2a
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    别名

    CDK2

    背景

    Background: CDK2, Cyclin-Dependent Kinase2, is also known as P33. The CDK2 protein was highly homologous to p34(CDC2) kinase and more significantly homologous to Xenopus Eg1 kinase, suggesting that CDK2 is the human homolog of Eg1. The CDK2 gene is mapped to 12q13, the same region to which the CDK4 gene maps. Human cyclin A binds independently to 2 kinases, p34(cdc2) or p33. In adenovirus-transformed cells, the viral E1A oncoprotein seems to associate with p33/cyclin A but not with p34(cdc2)/cyclin A. The gene for p33 shares 65 % sequence identity with p34(cdc2). P33(cdk2) plays a unique role in cell cycle regulation of vertebrate cells.

    Gene Full Name: cyclin dependent kinase 2

    基因ID

    1017

    UniProt

    P24941

    途径

    PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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