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Cyclin D3 抗体 (AA 136-292) (Fluoro550)

This 兔 多克隆 antibody specifically detects Cyclin D3 in FACS. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN7982190
发货至: 中国
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Quick Overview for Cyclin D3 抗体 (AA 136-292) (Fluoro550) (ABIN7982190)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

适用

  • 121
  • 42
  • 33
  • 16
  • 5
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  • 1
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 110
  • 14

克隆类型

  • 89
  • 35
多克隆

标记

  • 54
  • 7
  • 5
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
This Cyclin D3 antibody is conjugated to Fluoro550

应用范围

  • 88
  • 36
  • 36
  • 29
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  • 26
  • 16
  • 14
  • 13
  • 13
  • 9
  • 8
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 26
    • 16
    • 12
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 136-292

    原理

    Anti-Cyclin D3/CCND3 Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cyclin D3 shares 94%,93% amino acid (aa) sequences identity with mouse,rat Cyclin D3,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cyclin D3 recombinant protein (Position: Q136-L292). Human Cyclin D3 shares 94% and 93% amino acid (aa) sequences identity with mouse and rat Cyclin D3, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cyclin D3 (CCND3)

    别名

    CCND3

    背景

    Background: CCND3, also called Cyclin D3, is a protein that in humans is encoded by the CCND3 gene. It is mapped to 6p21.1. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. In addition, overexpression of CCND3 upregulated the translational activity in HeLa cells in a dose-dependent manner.

    Gene Full Name: cyclin D3

    Sequence Similarities: Belongs to the cyclin family. Cyclin D subfamily.

    基因ID

    896

    UniProt

    P30281

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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