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Cyclin A1 抗体 (AA 64-263)

This 兔 多克隆 antibody specifically detects Cyclin A1 in WB, IF, ICC 和 FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7982109
发货至: 中国
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Quick Overview for Cyclin A1 抗体 (AA 64-263) (ABIN7982109)

抗原

See all Cyclin A1 (CCNA1) 抗体
Cyclin A1 (CCNA1)

适用

  • 51
  • 47
  • 38
  • 18
  • 15
  • 5
  • 5
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 66
  • 21

克隆类型

  • 68
  • 19
多克隆

标记

  • 38
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This Cyclin A1 antibody is un-conjugated

应用范围

  • 66
  • 27
  • 19
  • 13
  • 13
  • 9
  • 9
  • 7
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

质量等级

Carrier-free
  • 抗原表位

    • 15
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 64-263

    原理

    Anti-Cyclin A1/CCNA1 Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cyclin A1 shares 78.5%,79.5% amino acid (aa) sequence identity with mouse,rat Cyclin A1,respectively.

    产品特性

    Anti-Cyclin A1/CCNA1 Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cyclin A1 recombinant protein (Position: D64-E263). Human Cyclin A1 shares 78.5% and 79.5% amino acid (aa) sequence identity with mouse and rat Cyclin A1, respectively.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Cyclin A1 (CCNA1)

    别名

    CCNA1

    背景

    Background: Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Also this cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: cyclin A1

    Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

    分子量

    52 kDa

    基因ID

    8900

    UniProt

    P78396

    途径

    Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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