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Cyclin A1 抗体 (AA 64-263) (APC)

This 兔 多克隆 antibody specifically detects Cyclin A1 in FACS. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7982106
发货至: 中国
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Quick Overview for Cyclin A1 抗体 (AA 64-263) (APC) (ABIN7982106)

抗原

See all Cyclin A1 (CCNA1) 抗体
Cyclin A1 (CCNA1)

适用

  • 51
  • 47
  • 38
  • 18
  • 15
  • 5
  • 5
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 66
  • 21

克隆类型

  • 68
  • 19
多克隆

标记

  • 39
  • 6
  • 5
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Cyclin A1 antibody is conjugated to APC

应用范围

  • 67
  • 27
  • 19
  • 13
  • 13
  • 10
  • 9
  • 8
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 15
    • 11
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 64-263

    原理

    Anti-Cyclin A1/CCNA1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cyclin A1 shares 78.5%,79.5% amino acid (aa) sequence identity with mouse,rat Cyclin A1,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cyclin A1 recombinant protein (Position: D64-E263). Human Cyclin A1 shares 78.5% and 79.5% amino acid (aa) sequence identity with mouse and rat Cyclin A1, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cyclin A1 (CCNA1)

    别名

    CCNA1

    背景

    Background: Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. The cyclin encoded by this gene was shown to be expressed in testis and brain, as well as in several leukemic cell lines, and is thought to primarily function in the control of the germline meiotic cell cycle. This cyclin binds both CDK2 and CDC2 kinases, which give two distinct kinase activities, one appearing in S phase, the other in G2, and thus regulate separate functions in cell cycle. Also this cyclin was found to bind to important cell cycle regulators, such as Rb family proteins, transcription factor E2F-1, and the p21 family proteins. Multiple transcript variants encoding different isoforms have been found for this gene.

    Gene Full Name: cyclin A1

    Sequence Similarities: Belongs to the cyclin family. Cyclin AB subfamily.

    基因ID

    8900

    UniProt

    P78396

    途径

    Apoptosis, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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