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Cullin 1 抗体 (N-Term) (HRP)

The HRP-conjugated 兔 多克隆 anti-Cullin 1 antibody (ABIN7981994) specifically detects Cullin 1 in WB, IHC 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7981994
发货至: 中国
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Quick Overview for Cullin 1 抗体 (N-Term) (HRP) (ABIN7981994)

抗原

See all Cullin 1 (CUL1) 抗体
Cullin 1 (CUL1)

适用

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人, 小鼠, 大鼠

宿主

  • 116
  • 1

克隆类型

  • 86
  • 31
多克隆

标记

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This Cullin 1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 15
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    • 1
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    N-Term

    原理

    Anti-Cullin 1/Cul1 Antibody HRP Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse,rat sequences.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human Cullin 1, identical to the related mouse and rat sequences.

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    Cullin 1 (CUL1)

    别名

    Cul1

    背景

    Background: Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.

    Gene Full Name: cullin 1

    Sequence Similarities: Contains 1 bHLH (basic helix-loop-helix) domain.

    UniProt

    Q13616

    途径

    Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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