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Cullin 1 抗体 (AA 457-770) (APC)

The 兔 多克隆 anti-Cullin 1 antibody is suitable to detect Cullin 1 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7981984
发货至: 中国
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Quick Overview for Cullin 1 抗体 (AA 457-770) (APC) (ABIN7981984)

抗原

See all Cullin 1 (CUL1) 抗体
Cullin 1 (CUL1)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Cullin 1 antibody is conjugated to APC

应用范围

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Flow Cytometry (FACS)
  • 抗原表位

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    AA 457-770

    原理

    Anti-Cullin 1/CUL1 Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human Cullin 1 shares 100% amino acid (aa) sequence identity with mouse Cullin 1.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Cullin 1 recombinant protein (Position: E457-D770). Human Cullin 1 shares 100% amino acid (aa) sequence identity with mouse Cullin 1.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cullin 1 (CUL1)

    别名

    CUL1

    背景

    Background: Cullin 1, also known as CUL1, is a human protein and gene from cullin family. This protein plays an important role in protein degradation and protein ubiquitination. This is an essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. Human cullin 1, but not the other closely related cullins 2, 3, 4A, and 5, selectively interacts with human SKP1.

    Gene Full Name: cullin 1

    Sequence Similarities: Belongs to the CCN family.

    UniProt

    Q13616

    途径

    Cell Division Cycle, Hedgehog Signaling, Mitotic G1-G1/S Phases, Regulation of Cell Size
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