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Cortactin 抗体 (AA 1-105) (Fluoro550)

The Fluoro550-conjugated 兔 多克隆 anti-Cortactin antibody (ABIN7981715) specifically detects Cortactin in FACS. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7981715
发货至: 中国
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Quick Overview for Cortactin 抗体 (AA 1-105) (Fluoro550) (ABIN7981715)

抗原

See all Cortactin (CTTN) 抗体
Cortactin (CTTN)

适用

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人, 小鼠, 大鼠

宿主

  • 144
  • 7
  • 1

克隆类型

  • 124
  • 28
多克隆

标记

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This Cortactin antibody is conjugated to Fluoro550

应用范围

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  • 5
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Flow Cytometry (FACS)
  • 抗原表位

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    AA 1-105

    原理

    Anti-Cortactin/CTTN Antibody Fluoro550 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human Cortactin recombinant protein (Position: M1-Q105).

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cortactin (CTTN)

    别名

    CTTN

    背景

    Background: Cortactin, mapped to 11q13.3, is a multidomain protein. This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

    Gene Full Name: cortactin

    UniProt

    Q14247

    途径

    MAPK Pathway
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