Complement Factor B 抗体 (AA 518-764) (PE)
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Quick Overview for Complement Factor B 抗体 (AA 518-764) (PE) (ABIN7981511)
抗原
See all Complement Factor B (CFB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 518-764
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原理
- Anti-Factor B/CFB Antibody PE Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- coli-derived human Factor B recombinant protein (Position: E518-L764). Human Factor B shares 84.2% amino acid (aa) sequence identity with mouse Factor B.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived human Factor B recombinant protein (Position: E518-L764). Human Factor B shares 84.2% amino acid (aa) sequence identity with mouse Factor B.
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亚型
- IgG
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anti-Complement Factor B (CFB) antibody
CFB 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 474-590) antibodyCFB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 34-159) antibodyCFB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 469-494) antibodyCFB 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21500 unconjugated
anti-Complement Factor B (CFB) (AA 26-751) antibodyCFB 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) antibodyCFB 适用: 人 IHC (p), ID 宿主: 山羊 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 301-400) antibodyCFB 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 32-157) antibodyCFB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Factor B (CFB) (AA 269-382) antibodyCFB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Complement Factor B (CFB)
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别名
- CFB
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背景
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Background: Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.
Gene Full Name: complement factor B
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基因ID
- 629
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UniProt
- P00751
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途径
- Complement System, Proton Transport, Ribonucleoside Biosynthetic Process
抗原
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