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C5 抗体 (C-Term) (Fluoro647)

The Fluoro647-conjugated 兔 多克隆 anti-C5 antibody (ABIN7981424) specifically detects C5 in FACS. The antibody is reactive with 大鼠 samples.
产品编号 ABIN7981424
发货至: 中国
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Quick Overview for C5 抗体 (C-Term) (Fluoro647) (ABIN7981424)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

  • 137
  • 67
  • 57
  • 20
  • 2
  • 2
  • 2
大鼠

宿主

  • 170
  • 23
  • 5
  • 4
  • 2
  • 1

克隆类型

  • 176
  • 29
多克隆

标记

  • 75
  • 18
  • 18
  • 14
  • 8
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This C5 antibody is conjugated to Fluoro647

应用范围

  • 89
  • 61
  • 50
  • 47
  • 46
  • 39
  • 18
  • 11
  • 11
  • 10
  • 7
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 24
    • 22
    • 15
    • 15
    • 13
    • 12
    • 12
    • 12
    • 12
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-C5/C5a Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross reactivity with other proteins

    预测反应

    different from the related mouse sequence by five amino acids.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of rat C5a, different from the related mouse sequence by five amino acids.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    C5

    背景

    Background: C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. The C5b macromolecular cleavage product can form a complex with the C6 complement component, and this complex is the basis for formation of the membrane attack complex, which includes additional complement components. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

    Gene Full Name: complement component 5

    Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

    基因ID

    362119

    UniProt

    P08650

    途径

    Complement System, Carbohydrate Homeostasis
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