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C5 抗体 (AA 1-77) (APC)

This 兔 多克隆 antibody specifically detects C5 in FACS. It exhibits reactivity toward 大鼠.
产品编号 ABIN7981389
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for C5 抗体 (AA 1-77) (APC) (ABIN7981389)

抗原

See all C5 抗体
C5 (Complement Component 5 (C5))

适用

  • 137
  • 67
  • 57
  • 20
  • 2
  • 2
  • 2
大鼠

宿主

  • 170
  • 23
  • 5
  • 4
  • 2
  • 1

克隆类型

  • 176
  • 29
多克隆

标记

  • 75
  • 18
  • 18
  • 14
  • 8
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This C5 antibody is conjugated to APC

应用范围

  • 89
  • 61
  • 50
  • 47
  • 46
  • 39
  • 18
  • 11
  • 11
  • 10
  • 7
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)
  • 抗原表位

    • 24
    • 22
    • 15
    • 15
    • 13
    • 13
    • 12
    • 12
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-77

    原理

    Anti-C5/C5a Antibody APC Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Rat C5a shares 62%,82% amino acid (aa) sequences identity with human,mouse C5a,respectively.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived rat C5a recombinant protein (Position: D1-R77). Rat C5a shares 62% and 82% amino acid (aa) sequences identity with human and mouse C5a, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    C5 (Complement Component 5 (C5))

    别名

    C5

    背景

    Background: C5a is a protein fragment released from complement component C5. This gene is mapped to 9q33.2. The protein encoded by this gene is the fifth component of complement, which plays an important role in inflammatory and cell killing processes. This protein is comprised of alpha and beta polypeptide chains that are linked by a disulfide bridge. An activation peptide, C5a, which is an anaphylatoxin that possesses potent spasmogenic and chemotactic activity, is derived from the alpha polypeptide via cleavage with a convertase. C5a plays a key role in increasing migration and adherence of neutrophils and monocytes to vessel walls. Mutations in this gene cause complement component 5 deficiency, a disease where patients show a propensity for severe recurrent infections. Defects in this gene have also been linked to susceptibility to liver fibrosis and to rheumatoid arthritis.

    Gene Full Name: complement component 5

    Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family.

    基因ID

    362119

    UniProt

    P08650

    途径

    Complement System, Carbohydrate Homeostasis
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