CSF3R 抗体 (Middle Region)
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北京 101111
Quick Overview for CSF3R 抗体 (Middle Region) (ABIN7981348)
抗原
See all CSF3R 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- Middle Region
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原理
- Anti-GCSF Receptor/CSF3R Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GCSF Receptor/CSF3R Antibody. Tested in WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor.
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亚型
- IgG
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anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 26-138) antibody
CSF3R 适用: 人 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-187) antibodyCSF3R 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8F8B12 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 271-428) antibodyCSF3R 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 25-187) antibodyCSF3R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3G10G2 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 252-280) antibodyCSF3R 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23568 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 117-337) antibodyCSF3R 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 101-200) antibodyCSF3R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 1-836) antibodyCSF3R 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) antibodyCSF3R 适用: 人 FACS 宿主: 小鼠 Monoclonal LMM741 unconjugated
anti-Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R) (AA 655-838) antibodyCSF3R 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Sodium azide, Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))
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别名
- CSF3R
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背景
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Background: CSF3R (Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114 ( (Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor (G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al. (1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al. (2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.
Gene Full Name: colony stimulating factor 3 receptor
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 2 subfamily.
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分子量
- 108 kDa
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基因ID
- 1441
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UniProt
- Q99062
抗原
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