M-CSF/CSF1 抗体 (AA 33-262) (HRP)
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Quick Overview for M-CSF/CSF1 抗体 (AA 33-262) (HRP) (ABIN7981256)
抗原
See all M-CSF/CSF1 (CSF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-262
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原理
- Anti-MCSF/CSF1 Antibody HRP Conjugated
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 %,88.6% amino acid (aa) sequence identity with human,rat MCSF,respectively.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.
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亚型
- IgG
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应用备注
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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有效期
- 12 months
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- Csf1
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背景
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Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Gene Full Name: colony stimulating factor 1 (macrophage)
Sequence Similarities: Contains 5 cadherin domains.
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基因ID
- 12977
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UniProt
- P07141
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途径
- RTK signaling
抗原
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