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CDSE1 抗体 (AA 1-775) (HRP)

The HRP-conjugated 兔 多克隆 anti-CDSE1 antibody (ABIN7980992) specifically detects CDSE1 in WB, IHC 和 ELISA. The antibody is reactive with 人 samples.
产品编号 ABIN7980992
发货至: 中国
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Quick Overview for CDSE1 抗体 (AA 1-775) (HRP) (ABIN7980992)

抗原

See all CDSE1 抗体
CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))

适用

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宿主

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克隆类型

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多克隆

标记

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This CDSE1 antibody is conjugated to HRP

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

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    AA 1-775

    原理

    Anti-CSDE1/NRU Antibody HRP Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CSDE1/NRU recombinant protein (Position: M1-Q775).

    亚型

    IgG
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CDSE1 (Cold Shock Domain Containing E1, RNA-Binding (CDSE1))

    别名

    CSDE1

    背景

    Background: Cold shock domain-containing protein E1 is a protein that in humans is encoded by the CSDE1 gene. Originally described as the product of an active transcription unit located upstream of the N-RAS gene, CSDE1 (cold shock domain-containing protein E1) is a highly conserved RNA-binding protein containing five cold-shock domains. CSDE1 is mostly localized in the cytoplasm where it interacts with distinct protein complexes involved in the post-transcriptional regulation of numerous mRNAs in a dynamic and complex manner. CSDE1 plays a role in maintaining the undifferentiated state of human embryonic stem cells (hESCs), and its loss results in accelerated neural differentiation and neurogenesis, partially via post-transcriptional regulation of fatty acid binding protein 7 (FABP7) and vimentin (VIM) mRNAs. In human melanoma, increased CSDE1 protein expression has been shown to modulate the levels of pro-oncogenic factors such as vimentin or RAC1 and tumor suppressors such as PTEN, thus promoting tumor invasion and metastasis.

    Gene Full Name: cold shock domain containing E1

    基因ID

    7812

    UniProt

    O75534

    途径

    SARS-CoV-2 Protein Interactome
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