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Cofilin 2 抗体 (C-Term)

The 小鼠 单克隆 anti-Cofilin 2 antibody is suitable to detect Cofilin 2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB, IHC, IF, FACS 和 ICC.
产品编号 ABIN7980895
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cofilin 2 抗体 (C-Term) (ABIN7980895)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

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人, 小鼠, 大鼠

宿主

  • 59
  • 17
  • 1
小鼠

克隆类型

  • 60
  • 17
单克隆

标记

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This Cofilin 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

质量等级

Carrier-free

克隆位点

8C13
  • 抗原表位

    • 28
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    C-Term

    原理

    Anti-Cofilin 2/CFL2 Antibody (monoclonal, 8C13)

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    预测反应

    identical to the related mouse sequence.

    产品特性

    Anti-Cofilin 2/CFL2 Antibody.(monoclonal, 8C13). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2/CFL2, identical to the related mouse sequence.

    亚型

    IgG2b
  • 应用备注

    Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunocytochemistry/Immunofluorescence, 2 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Cofilin 2 (CFL2)

    别名

    CFL2

    背景

    Background: Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

    Gene Full Name: cofilin 2

    分子量

    19 kDa

    基因ID

    1073

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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