Cofilin 2 抗体 (C-Term)
(1 reference)-
- 抗原 See all Cofilin 2 (CFL2) 抗体
- Cofilin 2 (CFL2)
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Cofilin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit polyclonal antibody to Cofilin 2 (cofilin 2 (muscle))
Cofilin 2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Cofilin 2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product CFL2 Primary Antibody
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anti-Cofilin 2 (CFL2) (AA 57-166) antibody
CFL2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 6G9 unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyVerified CFL2 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 121-153), (C-Term) antibodyCFL2 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-156) antibodyCFL2 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 130-144), (C-Term) antibodyCFL2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal RB48609 unconjugated
anti-Cofilin 2 (CFL2) antibodyCFL2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (AA 1-166) antibodyCFL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) (C-Term) antibodyCFL2 适用: 人, 小鼠, 大鼠, Pig, Cow, 马, 小鸡, 猴, Bat, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Cofilin 2 (CFL2) antibodyCFL2 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Raji , Neuro2A , C8D30 , Raw264.7
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins." in: International journal of molecular sciences, Vol. 20, Issue 22, (2020) (PubMed).
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: "Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins." in: International journal of molecular sciences, Vol. 20, Issue 22, (2020) (PubMed).
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- 抗原
- Cofilin 2 (CFL2)
- 别名
- cofilin 2 (CFL2 产品)
- 别名
- NEM7 antibody, CFL2 antibody, zgc:77288 antibody, cf12 antibody, cofilin 2 antibody, cofilin 2 (non-muscle) antibody, cofilin 2 (muscle) antibody, cofilin 2, muscle antibody, cofilin-2 antibody, CFL2 antibody, cfl2 antibody, Cfl2 antibody, cf12 antibody, LOC100359205 antibody
- 背景
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Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. (Gillett et al., 1996 [PubMed 8800436]). Cofilin-2 is a member of the AC group of proteins that also includes cofilin-1 (CFL1) and destrin (DSTN, MIM 609114), all of which regulate actin-filament dynamics (Bamburg et al., 1999 [PubMed 10461190], Maciver and Hussey, 2002). The CFL2 gene encodes a skeletal muscle-specific isoform (Vartiainen et al., 2002 [PubMed 11809832]) localized to the thin filaments, where it exerts its effect on actin, in part through interactions with tropomyosins (Ono and Ono, 2002 [PubMed 11901171]).[supplied by OMIM]
Cellular Localization: Nucleus matrix , Cytoplasm , cytoskeleton - 分子量
- 19 kDa
- 基因ID
- 1073
- UniProt
- Q9Y281
- 途径
- Caspase Cascade in Apoptosis
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