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Cofilin 2 抗体 (AA 1-166)

The 小鼠 单克隆 anti-Cofilin 2 antibody is suitable to detect Cofilin 2 in samples from 人.
产品编号 ABIN7858302
发货至: 中国
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Quick Overview for Cofilin 2 抗体 (AA 1-166) (ABIN7858302)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

  • 55
  • 25
  • 11
  • 5
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1

宿主

  • 48
  • 6
  • 1
小鼠

克隆类型

  • 49
  • 6
单克隆

标记

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  • 2
  • 2
  • 2
  • 1
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This Cofilin 2 antibody is un-conjugated

应用范围

请咨询

克隆位点

CFL2-9963
  • 抗原表位

    • 13
    • 9
    • 7
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    AA 1-166

    原理

    CFL2 / NEM7 Antibody

    特异性

    Cofilin is ubiquitously expressed in eukaryotic cells where it binds to Actin, thereby regulating the rapid cycling of Actin assembly and disassembly essential for cellular viability. Cofilin is a low molecular weight protein that binds to filamentous (F) Actin by bridging two longitudinally associated Actin subunits changing the F-Actin filament twist. This process is allowed by the dephosphorylation of Cofilin Ser-3 by factors such as opsonized zymosan. Lim kinase 1, a serine kinase, phosphorylates Cofilin and renders it unable to bind and depolymerise F-Actin.

    纯化方法

    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant fragment (around aa1-166) of human CFL2 protein (exact sequence is proprietary)

    亚型

    IgG1, kappa
  • 限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Prepared in 10  mM PBS

    储存液

    Azide free

    储存条件

    -20 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
  • 抗原

    Cofilin 2 (CFL2)

    别名

    CFL2

    背景

    NEM7

    分子量

    19-21kDa

    基因ID

    1073, 180141

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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