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Cofilin 2 抗体 (C-Term) (Fluoro647)

The 兔 多克隆 anti-Cofilin 2 antibody is suitable to detect Cofilin 2 in samples from 人, 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7980883
发货至: 中国
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Quick Overview for Cofilin 2 抗体 (C-Term) (Fluoro647) (ABIN7980883)

抗原

See all Cofilin 2 (CFL2) 抗体
Cofilin 2 (CFL2)

适用

  • 77
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  • 32
  • 5
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  • 2
  • 2
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  • 2
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  • 1
人, 小鼠, 大鼠

宿主

  • 58
  • 18
  • 1

克隆类型

  • 59
  • 18
多克隆

标记

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  • 5
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  • 2
  • 2
  • 1
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This Cofilin 2 antibody is conjugated to Fluoro647

应用范围

  • 43
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  • 9
  • 2
  • 2
  • 1
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Flow Cytometry (FACS)
  • 抗原表位

    • 28
    • 14
    • 9
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    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    C-Term

    原理

    Anti-Cofilin 2/CFL2 Antibody Fluoro647 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    identical to the related mouse sequence.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Cofilin 2, identical to the related mouse sequence.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Cofilin 2 (CFL2)

    别名

    CFL2

    背景

    Background: Cofilin 2 (muscle), also known as CFL2, is a protein which in humans is encoded by the CFL2 gene. It is mapped to 14q12. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. And this protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH -dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

    Gene Full Name: cofilin 2

    基因ID

    1073

    UniProt

    Q9Y281

    途径

    Caspase Cascade in Apoptosis
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