F2RL1 抗体 (C-Term)
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北京 101111
Quick Overview for F2RL1 抗体 (C-Term) (ABIN7980752)
抗原
See all F2RL1 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- Anti-PAR2/F2RL1 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse sequence by eight amino acids,and from the related rat sequence by seven amino acids.
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产品特性
- Anti-PAR2/F2RL1 Antibody. Tested in WB applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human PAR2, different from the related mouse sequence by eight amino acids, and from the related rat sequence by seven amino acids.
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亚型
- IgG
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anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 368-382), (C-Term), (Intracellular) antibody
F2RL1 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) antibodyF2RL1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 小鼠 Monoclonal AFfirm8664 unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (N-Term) antibodyF2RL1 适用: 人 IHC, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal SAM11 unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 348-397) antibodyF2RL1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人 WB, FACS 宿主: 兔 Monoclonal 23GB5850 unconjugated Recombinant Antibody
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (Extracellular Domain) antibodyF2RL1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (N-Term) antibodyF2RL1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人 ELISA, FACS, BLI, Func, SPR 宿主: Human Monoclonal PAR650097 unconjugated Recombinant Antibody
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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别名
- F2RL1
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背景
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Background: Protease activated receptor 2 (PAR2), also known as coagulation factor II (thrombin) receptor-like 1 (F2RL1) or G-protein coupled receptor 11 (GPR11), is a protein that in humans is encoded by the F2RL1 gene. F2RL1 is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. Additionally, PAR2 modulates inflammatory responses and acts as a sensor for proteolytic enzymes generated during infection.
Gene Full Name: F2R like trypsin receptor 1
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分子量
- 49 kDa
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基因ID
- 2150
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UniProt
- P55085
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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