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Claudin 3 抗体 (C-Term) (APC)

The 兔 多克隆 anti-Claudin 3 antibody is suitable to detect Claudin 3 in samples from 小鼠 和 大鼠. It has been validated for FACS.
产品编号 ABIN7980463
发货至: 中国
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Quick Overview for Claudin 3 抗体 (C-Term) (APC) (ABIN7980463)

抗原

See all Claudin 3 (CLDN3) 抗体
Claudin 3 (CLDN3)

适用

  • 102
  • 33
  • 28
  • 3
  • 3
小鼠, 大鼠

宿主

  • 91
  • 25
  • 1

克隆类型

  • 79
  • 38
多克隆

标记

  • 45
  • 10
  • 7
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
This Claudin 3 antibody is conjugated to APC

应用范围

  • 58
  • 38
  • 38
  • 28
  • 20
  • 19
  • 15
  • 5
  • 2
Flow Cytometry (FACS)
  • 抗原表位

    • 29
    • 26
    • 10
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Anti-Claudin 3/CLDN3 Antibody APC Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Claudin 3/CLDN3, which shares 73.3% and 94.1% amino acid (aa) sequence identity with human and rat Claudin 3/CLDN3, respectively.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    Claudin 3 (CLDN3)

    别名

    Cldn3

    背景

    Background: Claudin 3, also known as CLDN3, is a protein which in humans is encoded by the CLDN3 gene. This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens, and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane. This protein is highly overexpressed in uterine carcinosarcoma. This protein is also predominantly present in brain endothelial cells, where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology.

    Gene Full Name: claudin 3

    基因ID

    12739

    UniProt

    Q9Z0G9

    途径

    Hepatitis C
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