Chp2 抗体 (AA 1-196) (Fluoro488)
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北京 101111
Quick Overview for Chp2 抗体 (AA 1-196) (Fluoro488) (ABIN7979709)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-196
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原理
- Anti-CHP2 Antibody Fluoro488 Conjugated
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse,rat CHP2.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CHP2 recombinant protein (Position: M1-K196). Human CHP2 shares 81.6% amino acid (aa) sequence identity with both mouse and rat CHP2.
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亚型
- IgG
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应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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有效期
- 12 months
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- Chp2
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背景
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Background: This gene product is a small calcium-binding protein that regulates cell pH by controlling plasma membrane-type Na+/H+ exchange activity. This protein shares sequence similarity with calcineurin B and can bind to and stimulate the protein phosphatase activity of calcineurin A (CnA) and functions in the calcineurin/NFAT (nuclear factor of activated T cells) signaling pathway. Another member of the CHP subfamily, Calcineurin B homologous protein 1, is located on Chromosome 15 and is an inhibitor of calcineurin activity and has a genetic phenotype associated with Parkinson's Disease (OMIM:606988). This gene was initially identified as a tumor-associated antigen and was previously referred to as Hepatocellular carcinoma-associated antigen 520.
Gene Full Name: calcineurin like EF-hand protein 2
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基因ID
- 63928
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UniProt
- O43745
抗原
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