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Chp2 抗体 (Internal Region)

适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6258442
发货至: 中国
  • 抗原 See all Chp2 products
    Chp2
    抗原表位
    • 3
    • 1
    • 1
    • 1
    Internal Region
    适用
    • 14
    • 11
    • 11
    • 1
    人, 小鼠, 大鼠
    宿主
    • 12
    • 2
    克隆类型
    • 12
    • 2
    多克隆
    标记
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Chp2 antibody is un-conjugated
    应用范围
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
    特异性
    CHP2 Antibody detects endogenous levels of total CHP2.
    预测反应
    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CHP2, corresponding to a region within the internal amino acids.
    亚型
    IgG
  • 应用备注
    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Chp2
    Abstract
    Chp2 产品
    别名
    2010110P09Rik antibody, Cbhp2 antibody, chp-2 antibody, calcineurin-like EF hand protein 2 antibody, calcineurin like EF-hand protein 2 antibody, Chp2 antibody, CHP2 antibody
    背景

    Description: Functions as an integral cofactor in cell  pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing  pH and protecting cells from serum deprivation-induced death. Also plays a role in the regulation of cell proliferation and tumor growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus.

    Gene: CHP2

    分子量
    22 kDa
    基因ID
    63928
    UniProt
    O43745
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