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Choline Acetyltransferase 抗体 (AA 446-652)

This 兔 多克隆 antibody specifically detects Choline Acetyltransferase in WB 和 IHC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN7979607
发货至: 中国
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Quick Overview for Choline Acetyltransferase 抗体 (AA 446-652) (ABIN7979607)

抗原

See all Choline Acetyltransferase (CHAT) 抗体
Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

适用

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人, 小鼠, 大鼠

宿主

  • 135
  • 7
  • 4
  • 4
  • 2

克隆类型

  • 120
  • 32
多克隆

标记

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This Choline Acetyltransferase antibody is un-conjugated

应用范围

  • 77
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  • 8
  • 4
  • 3
  • 1
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Western Blotting (WB), Immunohistochemistry (IHC)

质量等级

Carrier-free
  • 抗原表位

    • 16
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    • 11
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    • 1
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    AA 446-652

    原理

    Anti-Choline Acetyltransferase/CHAT Antibody

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    Human CHAT shares 88.4%,87% amino acid (aa) sequence identity with mouse,rat CHAT,respectively.

    产品特性

    Anti-Choline Acetyltransferase/CHAT Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human CHAT recombinant protein (Position: D446-R652). Human CHAT shares 88.4% and 87% amino acid (aa) sequence identity with mouse and rat CHAT, respectively.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat, Human Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

    别名

    CHAT

    背景

    Background: Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.

    Gene Full Name: choline O-acetyltransferase

    分子量

    83 kDa

    基因ID

    1103

    UniProt

    P28329

    途径

    Skeletal Muscle Fiber Development
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