Choline Acetyltransferase 抗体
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- 抗原 See all Choline Acetyltransferase (CHAT) 抗体
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
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适用
- 人
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宿主
- 山羊
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克隆类型
- 多克隆
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标记
- This Choline Acetyltransferase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 交叉反应
- Bird (Avian), 小鸡, 豚鼠, 人, 小鼠, Non-Human Primate
- 交叉反应 （详细）
- Cross reactivity with ChAT from other species has not been determined
- 纯化方法
- Anti-ChAT antibody is directed against human ChAT protein. The antibody was affinity purified from monospecific antiserum by immunoaffinity purification. . However, reactivity is also expected from the following species based on 100% sequence homology: chicken, guinea pig, mouse, and non-human primates.
- 免疫原
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Immunogen: Anti-ChAT Antibody was produced in rabbit by repeated immunizations with native choline acetyltransferase purified from human placenta.
Immunogen Type: Native Protein
- 亚型
- IgG
- Top Product
- Discover our top product CHAT Primary Antibody
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anti-Choline O-Acetyltransferase (CHAT) (AA 517-732) antibody
CHAT 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) antibodyCHAT 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 331-630) antibodyCHAT 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 98-128) antibodyCHAT 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 101-200) antibodyCHAT 适用: 人, 小鼠, 大鼠, 犬 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 354-592) antibodyCHAT 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (C-Term) antibodyVerified CHAT 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) antibodyCHAT 适用: 人 WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) (AA 446-652) antibodyCHAT 适用: 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Choline O-Acetyltransferase (CHAT) antibodyCHAT 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistochemistry Dilution: 1:100
Application Note: Anti-ChAT antibody is suitable for use in ELISA, Western Blotting and IHC. Specific conditions for reactivity should be optimized by the end user. Expect a ~ 68/70 kDa band corresponding to choline acetyltransferase protein by Western Blot in the appropriate lysate or tissue.
Western Blot Dilution: 1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.01 M Sodium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 5 mg BSA
0.02 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.
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: "Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep." in: Nature, Vol. 548, Issue 7669, pp. 582-587, (2017) (PubMed).
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: "Lhx6-positive GABA-releasing neurons of the zona incerta promote sleep." in: Nature, Vol. 548, Issue 7669, pp. 582-587, (2017) (PubMed).
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- 抗原
- Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))
- 别名
- ChAT (Choline Acetyltransferase) (CHAT 产品)
- 别名
- CHOACTASE antibody, CMS1A antibody, CMS1A2 antibody, ChoAcTase antibody, B230380D24Rik antibody, choline O-acetyltransferase antibody, choline O-acetyltransferase a antibody, choline acetyltransferase antibody, carnitine O-acetyltransferase antibody, CHAT antibody, chata antibody, Chat antibody, PGTG_00551 antibody, LOC100533322 antibody
- 背景
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Synonyms: acetyl CoA:choline O-acetyltransferase, CHAT, CHOACTase, Choline acetylase, choline acetyltransferase, Choline O-acetyltransferase, CLAT, CMS1A, CMS1A2
Background: ChAT antibody recognizes choline acetyltransferase which is a neuronal enzyme which catalyzes the reaction between Acetyl CoA and choline resulting in the formation of acetylcholine. ChAT is found primarily in cholinergic neurons making it a valuable marker for diseases associated with decreased cholinergic function such as Schizophrenia, Alzheimer disease (AD) and Down syndrome. Decreased choline acetyltransferase activity in particular has been shown in Schizophrenic subjects. It has furthermore been demonstrated that in patients with AD, there are significantly lower levels of cortical ChAT that correlate with severity of the disease as measured by loss of neuropsychological function. Anti-ChAT antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research.
Gene Name: CHAT
- 基因ID
- 1103
- UniProt
- P28329
- 途径
- Skeletal Muscle Fiber Development
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