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CCR5 抗体 (Middle Region) (Cy3)

The 兔 多克隆 anti-CCR5 antibody is suitable to detect CCR5 in samples from 人. It has been validated for FACS.
产品编号 ABIN7978993
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for CCR5 抗体 (Middle Region) (Cy3) (ABIN7978993)

抗原

See all CCR5 抗体
CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

适用

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多克隆

标记

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This CCR5 antibody is conjugated to Cy3

应用范围

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Flow Cytometry (FACS)
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    Middle Region

    原理

    Anti-C-C chemokine receptor type 5 CCR5 Antibody Cy3 Conjugated

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human CCR5.

    亚型

    IgG
  • 应用备注

    Flow Cytometry, 1-3 μg/1x106 cells

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

    有效期

    12 months
  • 抗原

    CCR5 (Chemokine (C-C Motif) Receptor 5 (CCR5))

    别名

    CCR5

    背景

    Background: Human CC chemokine receptor 5 (CCR5), which is 17.5 kb from the CMKBR2 gene, encodes a 352-amino acid protein with a calculated molecular mass of 40,600 Da. It is organized into four exons and two introns. Human CCR5 is a co-receptor for macrophage-tropic strains of human immunodeficiency virus (HIV)-1 and is expressed by bone-marrow-derived cells. CCR5 is expressed on neurons, astrocytes, and microglia in the central nervous system, and on epithelium, endothelium, vascular smooth muscle and fibroblasts in other tissues. Functionally, CCR5 mediates the activation of cells by the chemokines macrophage inflammatory protein-1alpha, macrophage inflammatory protein-1beta, and RANTES, and serves as a fusion cofactor for macrophage-tropic strains of human immunodeficiency virus type 1.

    Gene Full Name: C-C motif chemokine receptor 5

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    基因ID

    1234

    UniProt

    P51681

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Cell Size
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