CCL4 抗体 (AA 24-92)
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北京 101111
Quick Overview for CCL4 抗体 (AA 24-92) (ABIN7978727)
抗原
See all CCL4 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- AA 24-92
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原理
- Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody
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特异性
- No cross reactivity with other proteins.
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交叉反应 (详细)
- No cross-reactivity with other proteins
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预测反应
- Rat CCL4 shares 80%,86% amino acid (aa) sequences identity with human,mouse CCL4,respectively.
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产品特性
- Anti-Macrophage Inflammatory Protein 1 beta/CCL4 Antibody. Tested in IHC, WB applications. This antibody reacts with Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived rat CCL4 recombinant protein (Position: A24-N92). Rat CCL4 shares 80% and 86% amino acid (aa) sequences identity with human and mouse CCL4, respectively.
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亚型
- IgG
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应用备注
- Western blot, 0.1-0.5 μg/mL, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Rat
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- CCL4 (Chemokine (C-C Motif) Ligand 4 (CCL4))
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别名
- CCL4
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背景
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Background: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in human is encoded by the CCL4 gene. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize CCL4. Based on functional analysis of CCL4, one or more additional beta chemokine receptors that transduce CCL4 signals must also exist. MIP-1alpha and CCL4 have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines (11, 14).
Gene Full Name: C-C motif chemokine ligand 4
Sequence Similarities: Belongs to the Wnt family.
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分子量
- 36 kDa
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基因ID
- 116637
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UniProt
- P50230
抗原
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