CCL2 抗体 (AA 24-99)
Our Local Distributor
北京 101111
Quick Overview for CCL2 抗体 (AA 24-99) (ABIN7978584)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
-
-
抗原表位
- AA 24-99
-
原理
- Anti-MCP1/CCL2 Antibody
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
预测反应
- coli-derived human MCP-1 recombinant protein (Position: Q24-T99). Human MCP-1 shares 60.9%,59.4% amino acid (aa) sequence identity with mouse,rat MCP-1,respectively.
-
产品特性
- Anti-MCP1/CCL2 Antibody. Tested in ELISA, IHC, WB applications. This antibody reacts with Human.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human MCP-1 recombinant protein (Position: Q24-T99). Human MCP-1 shares 60.9% and 59.4% amino acid (aa) sequence identity with mouse and rat MCP-1, respectively.
-
亚型
- IgG
-
-
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
-
别名
- CCL2
-
背景
-
Background: Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids. MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues. MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder. Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.
Gene Full Name: C-C motif chemokine ligand 2
Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.
-
分子量
- 11 kDa
-
基因ID
- 6347
-
UniProt
- P13500
-
途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
-