CDC45 抗体 (AA 166-431) (APC)
Our Local Distributor
北京 101111
Quick Overview for CDC45 抗体 (AA 166-431) (APC) (ABIN7977942)
抗原
See all CDC45 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 166-431
-
原理
- Anti-CDC45L Antibody (monoclonal, 6H6) APC Conjugated
-
交叉反应 (详细)
- No cross-reactivity with other proteins.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E. coli-derived human CDC45L recombinant protein (Position: E166-A431).
-
亚型
- IgG1
-
-
-
-
应用备注
- Flow Cytometry, Optimal dilutions should be determined by end users.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
-
有效期
- 12 months
-
-
- CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))
-
别名
- CDC45
-
背景
-
Background: CDC45 is a protein that in humans is encoded by the CDC45L gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.
Gene Full Name: cell division cycle 45
-
基因ID
- 8318
-
UniProt
- O75419
-
途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
-