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CDC45 抗体 (AA 166-431) (Biotin)

The Biotin-conjugated 小鼠 单克隆 anti-CDC45 antibody (Clone 6H6) (ABIN7977935) specifically detects CDC45 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN7977935
发货至: 中国
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Quick Overview for CDC45 抗体 (AA 166-431) (Biotin) (ABIN7977935)

抗原

See all CDC45 抗体
CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

适用

  • 81
  • 70
  • 67
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 77
  • 19
小鼠

克隆类型

  • 61
  • 35
单克隆

标记

  • 34
  • 6
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDC45 antibody is conjugated to Biotin

应用范围

  • 50
  • 40
  • 27
  • 26
  • 17
  • 13
  • 13
  • 12
  • 6
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

6H6
  • 抗原表位

    • 24
    • 15
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 166-431

    原理

    Anti-CDC45L Antibody (monoclonal, 6H6) Biotin Conjugated

    交叉反应 (详细)

    No cross-reactivity with other proteins.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived human CDC45L recombinant protein (Position: E166-A431).

    亚型

    IgG1
  • 应用备注

    Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

    有效期

    12 months
  • 抗原

    CDC45 (Cell Division Cycle 45 Homolog (S. Cerevisiae) (CDC45))

    别名

    CDC45

    背景

    Background: CDC45 is a protein that in humans is encoded by the CDC45L gene. The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Alternate splicing results in multiple transcript variants.

    Gene Full Name: cell division cycle 45

    基因ID

    8318

    UniProt

    O75419

    途径

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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